A Prevalence Of Hiv, Hbv and Hcv In Patients of Thalassemia

Dr. Payal Soni; Dr. Nisarg Trivedi; Dr. Parevee Shah; Dr. Dipa Kinariwala; Dr. Sumeeta Soni; Dr. P. K. Shah

Volume : III, Issue : IX, September - 2014

A Prevalence Of Hiv, Hbv and Hcv In Patients of Thalassemia

Dr. Payal Soni, Dr. Nisarg Trivedi, Dr. Parevee Shah, Dr. Dipa Kinariwala, Dr. Sumeeta Soni, Dr. P. K. Shah

Abstract :

Introduction : Thalassemia is one of the commonest inherited hemolytic disorder.1 Mainstay of management of thalassemics is 2–4 weekly packed red cell transfusion.Most common complication is transfusion transmitted infections.2The aim and objective of study is to determine the prevalence of HIV, Hepatitis B and Hepatitis C in thalassemia major children.2 Materials and methods : Present study was done at a tertiary care hospital in Ahmedabad, India from July 2012 to December 2012. Blood samples of 136 patients attending thalassemia clinics collected and tested by ELISA methods. Observations and results : A total of 136 thalassemic children (86 male) and 50 female) were tested.No one was HIV Positive, 2 (1.47%) were positive for HBsAg and 28 (20.58%) were positive for HCV. Incidence of anti–HCV seropositivity increases with no. of transfusions. Conclusion : Incidence of HIV and HBsAg has decreased due to mandatory screening of blood bags and vaccination of Hepatitis B.Screening of donor for HCV should be done by better recent techniques.