A PROSPECTIVE ANALYSIS OF EFFECT OF TERIPRATIDE ON FRACTURE HEALING IN OSTEOPOROTIC PERTROCHANTERIC FRACTURES

Dr. SriramThanigai; Dr.Dilip Kumar Naidu; Dr.Rajkumar

Volume : IV, Issue : VIII, August - 2015

A PROSPECTIVE ANALYSIS OF EFFECT OF TERIPRATIDE ON FRACTURE HEALING IN OSTEOPOROTIC PERTROCHANTERIC FRACTURES

Dr. Sriramthanigai, Dr. Dilip Kumar Naidu, Dr. Rajkumar

Abstract :

We prospectively analyzed the radiographic and clinical outcomes of osteoporotic pertrochantericfractures in 20 patients who underwent fixation with Cephalomedullary Device–Proximal Femur Nailing(PFN) and compared the results with 20 patients who received teriparatide in addition to PFN fixation. A significantly shorter time for fracture healing was recorded in the teriparatide–treated group than in the control group. Rates of Implant failure were significantly reduced in the teriparatide–treated group. There were no significant differences with regard to superficial wound infection, Respiratory complications,Mortality. The mean overall mobility scores were significantly better in the teriparatide–treated group at 3 and 6 months. The pain scores were also significantly better in the teriparatide–treated group at 3 and 6 months.Teriparatide improves radiographic outcomes and yields better clinical outcomes at 3 and 6 months postoperatively. The improvement in union time may be important for elderly populations with unstable pertrochanteric fractures to enable them to return to daily activities and reduce morbidity and mortality