Volume : VI, Issue : VII, July - 2017
A PROSPECTIVE RANDOMISED TRIAL TO COMPARE THE EFFICACY OF TOLTERODINE, SOLIFENACIN AND DARIFENACIN AS BLADDER RELAXANT
Singh Mayank, Rajkumar, Chaurasia Dilip, Singh Vinay Kumar
Abstract :
Aim: The aim of this study was to compare the relative efficacies as well as side effects of the three bladder smooth muscle relaxants, Darifenacin, Solifenacin and Tolterodine.
Methods: The study was a prospective randomised trial carried out in Surgery Department at M.L.N. Medical College, Allahabad from September 2010 to August 2013.
Results: Mean age of patients suffering from OAB was 44 years. To decrease the number of micturition episodes, efficacy of Solifenacin > Tolterodine > Darifenacin. To decrease urgency, efficacy of Solifenacin = Tolterodine > Darifenacin. For mixed incontinence Solifenacin was better than both Darifenacin and Tolterodine. Regarding nocturia, efficacy of Solifenacin = Darifenacin > Tolterodine. Most common side–effects associated with these drugs were dry mouth, constipation and blurred vision but latter was significantly less with Solifenacin.
Conclusion: For treatment of overactive bladder Solifenacin can be suggested as the first line drug.
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DOI : 10.36106/ijsr
Cite This Article:
Singh Mayank, Rajkumar, Chaurasia Dilip, Singh Vinay Kumar, A PROSPECTIVE RANDOMISED TRIAL TO COMPARE THE EFFICACY OF TOLTERODINE, SOLIFENACIN AND DARIFENACIN AS BLADDER RELAXANT, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-7 | JULY-2017
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Singh Mayank, Rajkumar, Chaurasia Dilip, Singh Vinay Kumar, A PROSPECTIVE RANDOMISED TRIAL TO COMPARE THE EFFICACY OF TOLTERODINE, SOLIFENACIN AND DARIFENACIN AS BLADDER RELAXANT, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-7 | JULY-2017
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