Volume : VI, Issue : IV, April - 2017

A REVIEW ON NOVELTRENDS IN VESICULAR CARRIER FOR ENHANCED TRANSDERMAL DELIVERY: ETHOSOMES

Eswar Kumar. A

Abstract :

 Skin acts as a major target as well as a principal barrier for topical/transdermal drug delivery. Despite the many advantages of this system, the major obstacle is the low diffusion rate of drugs across the stratum corneum. One simple and convenient approach is application of drugs in formulation with elastic vesicles or skin enhancers. Ethosomes are novel non–invasive ethanolic phospholipids came into existence from 1997 which acts as skin enhancers and carries the drug across stratum corneum and make them available in deeper layers of skin. The ethosomes can be prepared by hot method, Cold method and optimized method. The evaluation parameters of ethosomes include visualization, vesicle size and zeta potential, entrapment efficiency. Ethosomes have been found to be much more efficient at delivering drug to the skin than either liposomes or hydroalcoholic solution. The comprehension of this review is to illuminate the main aspects of ethosomes such as structure, composition, mechanism of penetration, advantages, available marketed products etc.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

ESWAR KUMAR.A, A REVIEW ON NOVELTRENDS IN VESICULAR CARRIER FOR ENHANCED TRANSDERMAL DELIVERY: ETHOSOMES, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-4 | APRIL‾2017

Number of Downloads : 582

References :