IJSR - International Journal of Scientific Research

Dr. B. Srinu; Dr. S. Krishna Mohana Rao; Dr G. Swarnalatha Devi

Volume : VIII, Issue : VIII, August - 2019

A STUDY OF CLINICAL AND HAEMATOLOGICAL PARAMETERS IN PATIENTS OF MALARIA AT TERTIARY TEACHING HOSPITAL

Dr. B. Srinu, Dr. S. Krishna Mohana Rao, Dr G. Swarnalatha Devi

Abstract :

INTRODUCTION: Malaria, the most important of the parasitic diseases of humans, transmitted in 106 countries containing 3 billion people and causes approximately 2000 deaths each day. AIMS AND OBJECTIVES:Asses the clinical severity of Malaria and its relation to hematologic and coagulation parameters.To determine the hematological parameters in patients with malaria. MATERIALS AND METHODS: STUDY DESIGN: An Analytical – Cross sectional study, which was conducted through clinical examination and laboratory investigation, in a tertiary health care center. PERIOD OF STUDY: The study was conducted for a period of 20 months, i.e., 2017 to 2019. STUDY AREA: The study was conducted in the department of General Medicine, Alluri Sitaram Raju Academy of Medical Sciences, Eluru, West Godavari district, Andhra Pradesh. INCLUSION CRITERIA: All cases positive for Malaria above 18 years of age were included in the study. EXCLUSION CRITERIA: All cases below the age of 18 years of age were excluded from the study. RESULTS: In this study the predominant age group affected was the age group between 18 to 30 years. The male to female ratio was 2.57:1. 41.2 % of patients had P. falciparum infection.32.4% of patients had P. Vivax infection. 26.5% of patients had mixed. Fever was the most common symptom and was present in nearly all cases.P. falciparum infection had more symptoms when compared to P. vivax. Symptoms and signs such as chills and rigors, easy fatigability, abdominal pain, vomiting, oliguria and altered sensorium have statistically significant association with malaria. CONCLUSION: The study concludes that P. Falciparum as well as P. Vivax can cause significant haematological changes with high occurrence of thrombocytopenia, anaemia, neutrophilia, monocytopenia and lymphopenia.