Volume : IV, Issue : VIII, August - 2015

A Study of Clinical profile and outcome of acute pancreatitis

Dinesh H N, Kiran Kumara Shetty

Abstract :

Background: Acute pancreatitis is defined as an inflammatory process of the pancreas with possible peripancreatic tissue and multi–organ involvement inducing multi–organ dysfunction syndrome(MODS) with increased mortality rate. Acute pancreatitis may be categorized as mild or severe. Mild acute pancreatitis is characterized by interstitial edema of the gland and minimal organ dysfunction. Severe acute pancreatitis is characterized by pancreatic necrosis, severe systemic inflammatory response and aften multi–organ failure. This study includes clinical presentation and complication and outcome of management of acute pancreatitis in our institute. Methods:We designed a prospective hospital based time bound study. Data were collected from 01–06–2013 to 31–12–2014. The study population consisted of 40 cases of acute pancreatitis those who fulfilled the diagnostic criteria. This was based on the UK guidelines for management of acute pancreatitis. Results: Out of 40 patients included in study , predominantly were males 33(82.5%) and 7(17.5%) were females. Majority were belonging to age group of 41–60(45%) with median age of 49.5 yrs. Most common etiology for acute pancreatitis was biliary followed by alcoholism(37.5%). Hyperlipidemia(2.5%) and traumatic (2.5%) pancreatitis was found in one patient each and where no cause was found labeled as idiopathic(12.5%). In our study Biliary pancreatitis was sole cause of pancreatitis in females(100%). In males alcoholism induced pancreatitis (45.45%) was most common, second commonest was biliary etiology. Conclusion: Males are predominantly affected. Alcoholism(45.45%) is the most common etiology among them followed by biliary etiology(33.30%). Biliary pancreatitis was sole cause of acute pancreatitis in females(100%). Majority of patients were belonging to age group of 41– 60(45%). In our study Diabetes mellitus(67.5%) was most common associated comorbidity followed by alcoholism(45%) and obesity(27.5%). Timely intervention by endoscopist and surgeons are crucial to reduce morbidity mortality

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dinesh H N, Kiran Kumara Shetty A Study of Clinical Profile and Outcome of Acute Pancreatitis International Journal of Scientific Research, Vol : 4, Issue : 8 August 2015

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