Volume : III, Issue : XII, December - 2014

A Study of Clinical Profile of Acute Respiratory Distress Syndrome

Dr. Z. H. Mansuri

Abstract :

Objectives : Many studies have been published in western literature on acute respiratory distress syndrome (ARDS). There are very few studies on the pattern of ARDS seen in Indian population. The study was carried out to identify the clinical pattern of Indian patients who died of ARDS. Methods : This was a retrospective study comprising of 49 patients who died of ARDS in the intensive care unit of a tertiary care referral centre. The present study looked at only those patients who died from ARDS and did not evaluate the clinical outcome or survival pattern of ARDS patients. The criteria used for diagnosis of ARDS was based upon American/European consensus statement for definition of acute lung injury(ALI) and ARDS. Results : There were 49 patients during the study period who died of ARDS. 27 males and 22 female patients. Thirteen patients had primary pulmonary infection, 9 had severe sepsis with multiorgan failure, 6 patients had polytrauma and 5 each had recent abdominal surgery and pancreatitis. Length of ICU stay was less than 10 days in 29 patients whereas in 20 patients it was more than 10 days. Duration of mechanical ventilation was less than seven days in 40 patients and more than seven days in 9 patients. Positive body fluid cultures were obtained in 21 out of 98 patients and of these, 7 patients had microbiological diagnosis established by blood culture, another 7 by endotracheal secretion culture, 4 by urine culture and in the remaining 3 patients based upon wound cultures. The commonest organisms isolated from the body fluids were Pseudomonas and Klebsiella. Conclusion : Primary pulmonary infection was associated with ARDS is one-third of patients. Multiorgan failure was seen in 18% of patients who died from ARDS. Severe sepsis was identified as a signifcant risk factor for ARDS.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

DR. Z. H. MANSURI A Study of Clinical Profile of Acute Respiratory Distress Syndrome International Journal of Scientific Research, Vol : 3, Issue : 12 December 2014

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