Volume : VII, Issue : V, May - 2018

A Study of DNA Damage in the Saliva of Oral Squamous Cell Carcinoma

Yugantar Wakde, Gaikwad S. B, M. G. Muddeshwar

Abstract :

Oral cancer is a sub–type of head and neck cancer, which is any cancerous tissue growth located in the oral cavity. India has highest incidence of OSCC in the world. The development of human cancer is depending on several factors such as DNA damage and DNA repair system. SCGE is used for measuring low level of strand eaks with high sensitivity in cells. The study consists of 115 OSCC patients and 45 control subjects. This study found that, as the severity of OSCC increases, the DNA damage proportionally increases which is marked by MTM. The increased level of MTM significantly in OSCC patient than the healthy controls, indicates that severe DNA damage occurs in OSCC patients during disease progression.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Yugantar wakde, Gaikwad S. B, M.G.Muddeshwar, A Study of DNA Damage in the Saliva of Oral Squamous Cell Carcinoma, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-5 | May-2018

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