A study of estimated glomerular filtration rate in diabetic patients in an Indian metro city

Dr.R.Shanker.MD; Dr.Hemalatha Shanker.MBBS; D.cos

Volume : IV, Issue : II, February - 2015

A study of estimated glomerular filtration rate in diabetic patients in an Indian metro city

Dr. R. Shanker. Md, Dr. Hemalatha Shanker. Mbbs, D. Cos

Abstract :

Background End stage renal disease is very common in diabetic patients. Early diagnosis using estimated glomerular filtration rate (eGFR) is helpful in management. Objective To assess eGFR associated with diabetes at a private clinic in an Indian metro city. Methods Patients attending a private clinic in Chennai were enrolled. Prevalence of diabetes was assessed by using fasting and postprandial blood sugar levels. eGFR values were calculated using formula provided by Modification of Diet in Renal Disease (MDRD) study group. Data was analyzed using appropriate statistical tests. Results Out of the 274 patients in whom further analysis was done, 62 patients had blood sugar levels higher than those required for diagnosis of diabetes. About 23 percent of the enrolled patients were diagnosed to be suffering from diabetes. Mean serum levels of creatinine in the diabetic patients was found to be 1.04 � 0.26 mg%. Mean serum creatinine concentration in diabetic males was 1.05 � 0.46 mg%, while mean creatinine concentration in females was found to be 0.95 � 0.42 mg%. However, creatinine values were in the normal range in majority of the patients i.e. diabetics as well as non-diabetics. On estimation of GFR in the diabetic patients it was found that mean GFR was 73.14 � 27.04 ml/ min/1.73sq.m. Mean GFR level in the diabetic males was 78.15 � 16.8 ml/ min/1.73sq.m while mean GFR levels in the diabetic females was 68.08 � 18.9 ml/ min/1.73sq.m. Difference was found to be statistically significant on comp� the two genders for serum creatinine as well as eGFR (p<0.05). 50 patients had stage 1 or 2 renal disease.