A Study of Hepatic Fibrosis in Chronic Liver Disease Patients Using Non-Invasive Methods of APRI Score and Transient Elastography

Dr Amar Patil; Dr Pradnya Diggikar; Dr P K Satpathy; Dr Anuja Patil; Dr Shubham Mishra

Volume : VIII, Issue : IX, September - 2019

A Study of Hepatic Fibrosis in Chronic Liver Disease Patients Using Non-Invasive Methods of APRI Score and Transient Elastography

Dr Amar Patil, Dr Pradnya Diggikar, Dr P K Satpathy, Dr Anuja Patil, Dr Shubham Mishra

Abstract :

Background: APRI and Transient elastography is recommended as the preferred non–invasive test to assess for the presence of cirrhosis (APRI score >2 in adults) in resource–limited settings. The present study was planned with an objective to study hepatic fiosis in chronic liver disease patients using non–invasive methods of APRI score and transient elastography. Methodology: The present study was a Cross–sectional Study conducted on cases with Chronic liver disease. The demographic details like age, gender, aetiology and duration of disease were recorded. Patients were assessed using APRI score and Transient Elastography. Stiffness is measured in terms of �liver fiosis index, and �strain ratio�. Results: It was seen that there was a positive correlation between APRI and LF index with correlation coefficient(r) of 0.30033 (p<0.05) and APRI and Strain index with correlation coefficient(r) of 0.2924 (p<0.05). While studying the diagnostic importance of APRI index, it was observed that it has a sensitivity of 87.50% while specificity of 35.29%. Conclusion: Transient elastography and APRI score are promising non–invasive methods, complementary to each other and can be used to detect the presence and extent of fiosis in chronic liver disease. APRI score is a sensitive but not a specific test to detect fiosis in patients of chronic liver disease.