A STUDY OF L CARNITINE SUPPLEMENTATION ON CLINICAL, SYSTOLIC AND DIASTOLIC FUNCTION OF LEFT VENTRICLE IN PATIENTS OF HEART FAILURE

Sanjay Beniwal; Balbir Singh Pachar; Anita Beniwal; Babu Lal Meena; Kulvinder Singh; Veer Bahadur Singh

Volume : IV, Issue : XI, November - 2015

A STUDY OF L CARNITINE SUPPLEMENTATION ON CLINICAL, SYSTOLIC AND DIASTOLIC FUNCTION OF LEFT VENTRICLE IN PATIENTS OF HEART FAILURE

Sanjay Beniwal, Balbir Singh Pachar, Anita Beniwal, Babu Lal Meena, Kulvinder Singh, Veer Bahadur Singh

Abstract :

 Objective: This study was carried out in north–west part of Rajasthan to investigate clinical effects of supplementation of L–carnitine in patients of heart failure. Material & Methods: Total 69 patients of heart failure were clinically assessed, NYHA classification of heart failure and standard echocardiography technique were applied before treatment with L–carnitine and at the 1st month and then subsequently on third months of the treatment. Results: 47 patients improved symptomatically by at least one functional class of NYHA and 21 patients showed no response and 1 patients worsened. The diameter of the left ventricular end–systolic, end–diastolic and EPSS have decreased with L–carnitine treatment (p<0.05). Decrease was observed in the left ventricular end–systolic and end–diastolic volumes (p<0.05), and an increase was also observed in the ejection fraction and myocardial fractional shortening. No significant change occurred in the diastolic function of the left ventricle. Conclusion: As a conclusion, supplementation of L–carnitine to the conventional therapy can give successful clinical results and improvement in systolic functions of heart.