A STUDY OF PREVALENCE OF HELICOBACTER  PYLORI INFECTION IN DIABETIC AND NONDIABETIC PATIENTS WITH DYSPEPTIC SYMPTOMS

Dr B Ananthi; Dr M Ramakumar

Volume : V, Issue : XII, December - 2016

A STUDY OF PREVALENCE OF HELICOBACTER PYLORI INFECTION IN DIABETIC AND NONDIABETIC PATIENTS WITH DYSPEPTIC SYMPTOMS

Dr B Ananthi, Dr M Ramakumar

Abstract :

Background: Infection with Helicobacter pylori is common worldwide and a significant cause of upper gastrointestinal disease. Recent reports suggested that Helicobacter pylori might have high prevalence among patients with diabetes. Aim: To determine the prevalence of Helicobacter pylori infection in diabetic and non–diabetic patients and to compare the prevalence of Helicobacter pylori infection in both groups. Materials and Methods: This hospital based case control study was conducted on 184 adult patients with dyspeptic symptoms for more than one month who were referred to the surgical endoscopic ward in ACS Medical College and Hospital. Fasting blood sugar was checked in all these patients and according to American Diabetes Association criteria they were divided into two groups Group I Diabetics and Group II Non Diabetics. Each group consists of 92 patients. All these diabetic and nondiabetic patients were then screened for Helicobacter pylori infection by doing the Imunocard test (SD Bioline). Results: Among the diabetic group Helicobacter pylori was positive in 61/92 (66.30%), whereas in the nondiabetic group Helicobacter pylori was positive in 21/92 (22.82%). Age–wise distribution of Helicobacter pylori positive patients showed prevalence rate progressively increased with age in both diabetic and nondiabetic groups with a high prevalence rate in 40 to 49 age group in both diabetic (31.15%) and nondiabetic (33.33%) groups. Thereafter prevalence rate decreased gradually in older age in both groups. Males were predominantly affected as compared to females in both diabetic and nondiabetic groups. Conclusion: Diabetic patients are more prone and at risk to acquire Helicobacter pylori infection. So every diabetic patients with dyspeptic symptoms should be screened for Helicobacter pylori.