A Study of Treatment Outcomes of Tuberculosis in patients with Type II Diabetes Mellitus.

Nilesh Agrawal; Dr. Pranay Gandhi; Sunita Sharma

Volume : III, Issue : X, October - 2014

A Study of Treatment Outcomes of Tuberculosis in patients with Type II Diabetes Mellitus.

Nilesh Agrawal, Dr. Pranay Gandhi, Sunita Sharma

Abstract :

AIMS: To compare treatment outcomes among TB patients with diabetes with those without diabetes. SETTING AND DESIGN: Study was conducted in a tertiary care centre in central India, among patients registered with Revised National TB Control Programme. Prospective observational study design was used. MATERIALS AND METHODS: Registered TB patients aged 30 and above were invited to participate in the study. Those who were not aware of their diabetic status were diagnosed using oral glucose tolerance test. A total of 89 diabetic and 120 non–diabetic patients were recruited in the study. RESULTS: Bi–variate (unadjusted) analysis showed similar treatment success rates in the two groups. But adjusted odds ratios for successful treatment among diabetic patients were significantly lower (0.191, 95% CI 0.04–0.90) for pulmonary TB patients and for smear positive pulmonary TB patients (odds ratio 0.099, 0.013–0.761). CONCLUSIONS: Diabetes increases risk of poor treatment outcomes among pulmonary TB patients