A Study of Twenty Four Hour Intraocular Pressure and Blood Pressure pattern Associated With Early Glaucomatous Changes.

Dr. Vimlesh Sharma; Dr Shanti Pandey; Dr. Pravin Hankare; Dr Bhaskar Painyuli; Dr Govind Singh Tityal

Volume : IX, Issue : V, May - 2020

A Study of Twenty Four Hour Intraocular Pressure and Blood Pressure pattern Associated With Early Glaucomatous Changes.

Dr. Vimlesh Sharma, Dr Shanti Pandey, Dr. Pravin Hankare, Dr Bhaskar Painyuli, Dr Govind Singh Tityal

Abstract :

Purpose: To observe the diurnal variation of intraocular pressure with blood pressure in patients with early glaucomatous changes. Material and methods: This study was conducted on 128 patients over a period of 1 year, they were divided into two, age and sex matched groups, out of which 64 patients were in control group with healthy disc and 64 patients were with early glaucomatous disc changes. IOP and blood pressure was measured for a period of 24 hours at the interval of 2 hours. Mean diurnal IOP, MOPP and blood pressure were compared with each group. Results: Mean diurnal IOP was significantly higher in the glaucomatous disc patients. Mean nocturnal IOP was higher than mean diurnal IOP. Early morning hours, the IOP increased in the patients having glaucomatous disc changes. There was a diurnal decrease in mean blood pressure. Conclusion: There was high diurnal IOP, the diurnal–to–nocturnal change of IOP is less, and the IOP pattern around normal awakening time is different in eyes with early glaucomatous changes. Circadian fluctuation of ocular perfusion pressure may be a contributing factor in the pathogenesis of glaucomatous optic neuropathy.