Volume : VII, Issue : XI, November - 2018

A STUDY ON HEALTH RELATED QUALITY OF LIFE IN PATIENTS WITH THYROID DISORDERS.

K. Rakesh Reddy, Sudeep. K, Venkatesha. B. M

Abstract :

 

BACKGROUND:

Thyroid diseases affect quality of life (QOL) 1. The Thyroid–Related Patient–Reported Outcome (ThyPRO) is an international comprehensive well–validated patient–reported outcome, measuring thyroid–related QOL. The purpose of the present study was to know the effects of thyroid disorders on quality on life.

METHODS:

A cross–sectional study (N = 100) of thyroid patients were analyzed. A graded item response theory (IRT) model was fitted to the cross–sectional data. Short–form scales with three items and Seven scales measuring mental and social well–being and function as well as one overall QOL impact item were analyzed in a bifactor model, to develop a supplementary composite score. The short and long form was estimated by agreement plots, intraclass correlations, and mean score levels. Responsiveness was compared by relative validity indices, clinical validity by ability to detect clinically relevant differences, and test–retest reliability by intra–class correlation.

RESULTS:

A bifactor model with good overall fit was fitted to the composite score, including the single QoL item. Short– versus long–form intraclass correlations were high (0.89–0.98), and the mean scale levels were similar.Mood/behaviour disturbances were present in a large proportion of patients and were significantly associated with poor QOL.

CONCLUSIONS:

A comprehended version of the questionnaire, with good measurement properties, was developed and is recommended for clinical use.QOL was significantly reduced in patients with thyroid diseases.Perceived health status may be considered as an additional outcome of management and therapy of thyroid disorders.

Keywords :

Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

A STUDY ON HEALTH RELATED QUALITY OF LIFE IN PATIENTS WITH THYROID DISORDERS. , K. Rakesh Reddy, Sudeep. K, Venkatesha. B. M , INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7|Issue-11| November-2018


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