A STUDY ON SEROLOGICAL PREVALENCE AND CLINICAL CORRELATION OF DENGUE IN A TERTIARY CARE HOSPITAL

Dr.C.S.Sripriya; Dr.Thasneem Banu.S; Dr.P Balapriya; Dr.S.Gitalakshmi

Volume : V, Issue : VII, July - 2016

A STUDY ON SEROLOGICAL PREVALENCE AND CLINICAL CORRELATION OF DENGUE IN A TERTIARY CARE HOSPITAL

Dr. C. S. Sripriya, Dr. Thasneem Banu. S, Dr. P Balapriya, Dr. S. Gitalakshmi

Abstract :

BACKGROUND: Dengue is a flaviviral infection occurring worldwide. In tropical region, Its distribution is determined by the presence of principal mosquito vector, Aedes aegypti. Early case detection in dengue cases and management reduces morbidity and mortality due to Dengue haemorrhagic fever and dengue shock syndrome. OBJECTIVE: To determine the seropositivity of dengue and to categorize dengue cases as Dengue fever, Dengue haemorrhagic fever and Dengue shock syndrome according to WHO guidelines and to evaluate the proportion of primary and secondary dengue infection based on anti–dengue IgM and I gG antibodies. MATERIALS AND METHODS: A total of 296 samples collected from patients with feile illness suspected of dengue were subjected to Denue IgM capture Enzyme Linked Immunosorbent assay (ELISA) and Dengue IgG capture ELISA. RESULTS: Among the samples tested ,39 cases were positive for IgM,22 positive for IgG and 41 positive for both IgM and IgG.Based on IgM: IgG ratio,30 cases had primary dengue infection and 72 had secondary dengue infection