A Study On The Serum �-HCG And Lipid Profile In Early Second Trimester As A Predictor Of Pregnancy Induced Hypertension

Dr. Roshan Lal Darangi; Dr. Susheela Khoiwal

Volume : IX, Issue : VI, June - 2020

A Study On The Serum �-HCG And Lipid Profile In Early Second Trimester As A Predictor Of Pregnancy Induced Hypertension

Dr. Roshan Lal Darangi, Dr. Susheela Khoiwal

Abstract :

BACKGROUND: Pregnancy is nature�s precious gift utilizing its 9 month of duration in achieving good maternal and fetal outcome. There are several complications that may impair a favourable pregnancy outcome. AIM AND OBJECTIVES: The study aims at testing the hypothesis that women with high serum beta hcg levels and lipid profile in early second trimester have high risk of developing pregnancy induced hypertension. MATERIAL AND METHODS: This prospective study was conducted on 150 pregnant women attending the antenatal clinic of the department of Obstetrics and Gynaecology at RNT Medical College Hospital Udaipur, Rajasthan as well as those visit in ANC and admitted in the ward were selected for the study. RESULTS: 110 (normal BMI) & 40 were BMI >30. Mean � S.D. triglyceride levels are below the normal values in this study in PIH patients (p–value 0.585). HDL levels are normal (85.33%) or decreased in (14.67%) of PIH patients (p<0.001). Increase in LDL is significant in developing preeclampsia. The mean beta HCG values is significantly more than normal values in our study (14 to 20 weeks) (p <0.001) highly significant. Beta HCG 25000 mIU/l used as a cut off value. CONCLUSION: The study showed that measuring second trimester beta HCG levels is useful in clinical practice to identify women who will develop PIH in the same pregnancy. The sample size for this study being small, necessitate the need of further large scale studies considering the importance of BETA–HCG in PIH prediction