Volume : VII, Issue : IV, April - 2018
A STUDY REPORT OF REPEATED DOSE 28-DAY ORAL TOXICITY STUDY OF NIRAPARA FRESH WASH IN WISTAR RATS
Dr. Shansasidharan, Dr. Sithara. M. S
Abstract :
Nirapara fresh wash is a natural formulation to clean the Vegetables, fruits and non–vegetableitems like fish, meat etc. Nirapara fresh wash help to remove dirt, toxins, microbes, heavy metals, pesticides and other foreign particles from vegetables/fruits and removes toxins, biological fluids ,microbes ,antibiotics, drugs (antibiotics and steroids), poisons,pesticides and other chemicals from non vegetable items. And it offers freshness to vegetables/fruits andnon–vegetable items.The product is not intended for direct oral consumption. It is only used for washing the vegetables /fruits and non–veg items.
Repeated dose 28–day oral toxicity study with 14 day reversal period of Nirapara Fresh Wash in Wistar Rats was conducted to evaluate the possible health hazards likely to arise fromrepeated exposure over a relatively limited period of time. The study was conducted in six groups consisting of 52 rats with 26 males and 26 females. The animals were observed for health status, clinical signs of toxicity and mortality. Body weights and food consumptions were recorded at weekly intervals. On completion of 28 days for treatment groups or 42 days for recovery groups respectively, the blood samples were collected from all the animals and subjected to haematological and clinical chemistry evaluation. At termination the animals were humanely sacrificed and subjected to necropsy. Histopathological examination was conducted on the specified list of tissues from the control and the treatment groups.From the above study the product is demonstrated its safety even for consuming directly by oral route.
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DOI : 10.36106/ijsr
Cite This Article:
Dr.ShanSasidharan, Dr. Sithara.M.S, A STUDY REPORT OF REPEATED DOSE 28–DAY ORAL TOXICITY STUDY OF NIRAPARA FRESH WASH IN WISTAR RATS, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-4 | April-2018
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Dr.ShanSasidharan, Dr. Sithara.M.S, A STUDY REPORT OF REPEATED DOSE 28–DAY ORAL TOXICITY STUDY OF NIRAPARA FRESH WASH IN WISTAR RATS, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-4 | April-2018
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