Volume : III, Issue : VI, June - 2014

Acid Catalyzed Hydrolysis of Di–2–Methoxy–4–Nitroaniline Phosphate

Homeshwari Yadav, Prof. Mrs. S. A. Bhoite

Abstract :

The hydrolysis of phosphate esters is one of the most fundamental chemical and biochemical reaction and their kinetic study deals all the significant aspects of chemical reactions including mechanism. In present investigation hydrolytic study of di-2-methoxy-4-nitroaniline phosphate has been carried out in 0.5-7.0 mol dm-3 HCl in 20% (v/v) dioxane-water medium at 70oC. The inorganic phosphate produced during hydrolysis has been determined spectrophotometrically using Allen’s modified method. The pseudo first order rate constants have been determined. The log rate profile shows rate maximum at 4.0 mol dm-3 HCl. The lowering of rate after 4.0 mol dm-3 HCl has been attributed to the effect of water activity. Ionic strength data is used to identify reactive species and find out theoretical rates. Bimolecular nature of the reaction has been decided by the Arrhenius, Bunnett & Bunnett-Olsen’s parameters and Zucker-Hammett hypothesis. The diester involves P-N bond fission, which is strengthened by comparative kinetic rate data. The probable reaction mechanism for the hydrolysis of diester via conjugate acid species has been suggested.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Homeshwari Yadav, Prof. (Mrs.) S. A. Bhoite / Acid Catalyzed Hydrolysis of Di-2-Methoxy-4-Nitroaniline Phosphate / International Journal of Scientific Research, Vol.3, Issue.6 June 2014

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