Acute kidney injury complicates advanced liver cirrhosis in hospitalized patients: causes and shortterm outcomes

Hind Fallatah; Hanadi Alhozali

Volume : V, Issue : X, October - 2016

Acute kidney injury complicates advanced liver cirrhosis in hospitalized patients: causes and shortterm outcomes

Hind Fallatah, Hanadi Alhozali

Abstract :

Acute kidney injury (AKI) is frequent complications in patients with advanced cirrhosis. This is a 12 month retrospective study of AKI and its associated factors in hospitalized patients with cirrhosis. For each patient, we performed initial renal function tests and electrolyte levels, at 48 hours post admission and at discharge. We also obtained all patient�s CBC. A total of 49 patients were included in the final analysis. The majority of patients were women (29, 59.2%), mean age was 53 years (SD, 16.5 ). The most common indication for admission was ascites (34 patients, 69.4%), and spontaneous bacterial peritonitis was present in half (17) of them. Baseline renal dysfunction was present in 21 (43%) patients, and 16 of these patients (32.65% of all patients) had AKI. The risk factors associated with the development of AKI were older age, hypoalbuminemia, elevated white blood cell (WBC) count, sepsis, and, hyponatremia (P=.022, .008, .033 and .06, respectively). Hypoalbuminemia was associated with persistent renal dysfunction at discharge. Conclusions: AKI is a common complications our cirrhotic patients, and some patients will not achieve complete renal function normalization after AKI