Acute Necrotizing Encephalopathy of Childhood: A case report from Katihar Medical College, Bihar, India.

Dr. Ashit Kumar; Prof. Dr. Ghazi Sharique Ahmad

Volume : VIII, Issue : XI, November - 2019

Acute Necrotizing Encephalopathy of Childhood: A case report from Katihar Medical College, Bihar, India.

Dr. Ashit Kumar, Prof. Dr. Ghazi Sharique Ahmad

Abstract :

Acute necrotizing encephalopathy of childhood (ANEC) previously thought as rare disease entity nearly exclusively seen in East Asian children including Japan and Taiwan. However, its sporadic cases have been reported from all over the world. The disease affects previously healthy young children and is characterized by respiratory or gastrointestinal infection, high grade fever accompanied by rapid alteration of consciousness and seizure. The hallmark of the disease is diffuse and symmetrical CNS lesions of thalami, ainstem, cerebellum, and white matter. The pathogenesis is still not known, most consider it secondarily after viral infection, however its genetic predisposition is also proposed. We were reported a case of 12 year old girl with ANEC hospitalized in Katihar Medical College and Hospital, Katihar and concluded that Acute Necrotizing Encephalopathy had poor outcome. And awareness for the detection of under diagnosed cases is needed to identify possible predisposing factors and improve the outcome of this dangerous acute illness of childhood.