Acute Pain: A Study of Intravenous Tramadol Hydrochloride Versus Bupivacaine Hydrochloride Irrigation Through Surgical Drains

Solanki Rekha N; Thakkar Jayshree M; Patel Bipin M; Makwana Yogesh C; Chauhan Arun S; Pol Dhiraj S

Volume : III, Issue : X, October - 2014

Acute Pain: A Study of Intravenous Tramadol Hydrochloride Versus Bupivacaine Hydrochloride Irrigation Through Surgical Drains

Solanki Rekha N, Thakkar Jayshree M, Patel Bipin M, Makwana Yogesh C, Chauhan Arun S, Pol Dhiraj S

Abstract :

Background Aims of the study were to determine the effects of bupivacaine irrigation in management of acute postoperative pain after radical surgery for east cancer and to study the twenty four hour dose requirement of tramadol after bupivacaine irrigation with its safety profile. Methods: This study was conducted in forty adult patients belonging to ASA I and II posted for elective modified radical mastectomy under general anaesthesia. They were randomly assigned into two groups of twenty each. Group B–10 ml of 0.4% bupivacaine in each drain 8 hourly. Group T–Intravenous infusion of tramadol at the rate of 0.25 mg/kg/hour. Postoperative pain scores, and side effects like nausea, vomiting, sedation, urinary retention, respiratory depression, pruritus, ECG, haemodynamic changes were monitored and requirement of additional rescue analgesic doses were noted. Results: Bupivacaine irrigation through surgical drains is a reasonably good technique for acute postmastectomy pain relief.It is associated with reduction in tramadol requirement by one fifth.(P–0.0004) Nausea, vomiting, sedation and respiratory depression are less in B group than in T group and are statistically significant.(P