AGENESIS OF THE AORTIC VALVE ASSOCIATED WITH HYPOPLASTIC LEFT VENTRICLE – A PATHOLOGIST‘S POINT OF VIEW

Adrian Dumitru; Alexandru Procop; Tiberiu–Augustin Georgescu; Mariana Costache; Monica Mihaela Cirstoiu; Adriana Elena Nica; Maria Sajin

Volume : VII, Issue : III, March - 2018

AGENESIS OF THE AORTIC VALVE ASSOCIATED WITH HYPOPLASTIC LEFT VENTRICLE – A PATHOLOGIST‘S POINT OF VIEW

Adrian Dumitru, Alexandru Procop, Tiberiu Augustin Georgescu, Mariana Costache, Monica Mihaela Cirstoiu, Adriana Elena Nica, Maria Sajin

Abstract :

Congenital aortic valve agenesis is a rare heart anomaly usually associated with other developmental cardiac malformations, part of the so–called �hypoplastic left–heart syndrome�. To the best of our knowledge, most reported cases of aortic valve atresia or agenesis have been associated with anomalies of the mitral valve, hypoplasia and/or coarctation of the ascending aorta, malformation of the left ventricle or the interventricular septum, patent foramen ovale and coronary abnormalities. These malformations are responsible for 25% to 40% of all neonatal cardiac deaths. We report a case of aortic valve agenesis associated with left ventricular fioelastosis found in a 25–week miscarried fetus, product of the first pregnancy of two non–consanguineous healthy parents, with no history of drug abuse or exposure to toxic or teratogenic agents