AIM: To study the clinical profile of patients with acute pyelonephritis presenting as acute kidney injury.

Harsh Vardhan; Amresh Krishna; Prit Pal Singh; Om Kumar; Govind Prasad

Volume : VII, Issue : II, February - 2018

AIM: To study the clinical profile of patients with acute pyelonephritis presenting as acute kidney injury.

Harsh Vardhan, Amresh Krishna, Prit Pal Singh, Om Kumar, Govind Prasad

Abstract :

Background: Acute pyelonephritis (APN) is an important cause of mortality and morbidity in the general population1.Acute kidney injury (AKI) is a known and important complication of APN. But there is a paucity of data on the exact incidence of AKI in APN. In this study we analysed the patients with acute pyelonephritis and acute kidney injury at our centre. Methods: We retrospectively collected clinical, biochemical and radiological data of patients hospitalized in nephrology ward of our institute with a diagnosis of APN with AKI from June 2016 to December 2017.We collected the records of 58 patients out of which 41 were selected for the evaluation as per our study criteria. Results: Among 41 patients, 32(78%) are male and 9 (22%) are female. Mean age of the patients is 46.56 � 15.8. Risk factors for pyelonephritis like diabetes mellitus, obstructive uropathy, renal calculi and renal transplant were present in 16 (39%), 14 (34.1%), 5 (12.2%) and 2 (4.9%) respectively. Emphysematous pyelonephritis was present in 6 patients (14.6%). 4 (66.6%) of them had diabetes and 2 patients (33%) had positive blood culture. Conclusions: Our data suggests that APN remains as an important cause of AKI which should be early diagnosed and promptly treated with almost complete recovery of renal function.