Volume : V, Issue : IX, September - 2016

An analysis of Whipple’s resection in tertiary care centre: Prognostic parameters revisited.

Dr Rima N Kamat, Dr Shilpa K Lad, Dr Arvind E Rathod, Dr Rajeev M Joshi

Abstract :

 Introduction: Whipple’s surgery remains the main stay of treatment for ampullary and periampullary tumours. This study was undertaken to study the demographic profile, prognostic parameters (lymphovascular invasion, perineural invasion, lymph node metastasis, resection margin involvement) in intestinal and pancreatobiliary carcinomas. Also, postoperative morbidity and mortality were studied in relation to various types of ampullary and periampullary carcinomas in patients where follow up was available. Methods – This is a retrospective study carried out over a decade in a tertiary care centre. Gross and histologic examination of 155 whipple’s specimens received during that tenure were reviewed. Follow up was obtained in 32 cases and evaluated with emphasis on perioperative mortality and morbidity. Results– Ampullary adenocarcinomas were the commonest tumours seen in our study. These were closely followed by distal common bile duct (CBD) and pancreatic tumours. There was a significant male preponderance with Male to female ratio of 1.6:1. Postoperative complications were seen in 21.2% cases with mortality seen in 7.9 % cases. Conclusion– Ampullary adenocarcinomas were commonest. Pancreatic adenocarcinomas showed high proportion of perineural, lymphovascular invasion and nodal metastasis. Tumours of distal CBD were more aggressive than other periampullary tumours.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr Rima N Kamat, Dr Shilpa K Lad, Dr Arvind E Rathod, Dr Rajeev M Joshi An analysis of Whipple¥s resection in tertiary care centre: Prognostic parameters revisited. International Journal of Scientific Research,Volume : 5 | Issue : 9 |September 2016

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