An Experimental Study of Cuminum Cyminum for its Analgesic Properties in Albino Rat

Dr. Kamal Kishore Khichi; Dr. Akhtar Ali; Dr. Anusuya Gehlot; Dr. Rajkumar Rathore

Volume : VIII, Issue : III, March - 2019

An Experimental Study of Cuminum Cyminum for its Analgesic Properties in Albino Rat

Dr. Kamal Kishore Khichi, Dr. Akhtar Ali, Dr. Anusuya Gehlot, Dr. Rajkumar Rathore

Abstract :

Aim: To evaluate the analgesic property of Cuminum Cyminum in albino rats. Methodology: We have conducted "tail–flick methods" on albino rats for analgesic activity, rats were divided into three groups for each parameter under study. Group I consisting of six animals, served as control and received distilled water. Group II subdivided into three groups II–A, II–B, II–C, consisting of six animals each, received Cuminum cyminum in three doses of 300mg, 750 mg, 1000mg per orally respectively. Group III subdivided into three groups III–A, III–B, III–C, consisting of six animals each, received the standard drug in three doses per orally. Result: Cuminum cyminum increased the reaction time which was variable with different doses and time periods (after 30, 60, 90 minutes of oral administration). At 30 minutes, the reaction time was not significant in a lower dose (300 mg per kg) while reaction time was highly significant in higher doses and after 60 and 90 minutes. Conclusion: Aqueous extract of Cuminum cyminum is having significant analgesic activity property in the albino rat. It could be highly significant but because extract got heat thermal degradation so it may be lost some of its property. However further study needed to find out its mechanism of actions and chemical constitutes responsible for this activities.