AN OBSERVATIONAL STUDY ON ETIOLOGICAL AND EPIDEMIOLOGICAL PROFILE OF CHRONIC LIVER DISEASE IN TERTIARY CARE HOSPITAL

Mohammad Amir Suhail; Ashish Kumar Verma; Dr. Amit Mishra; Prof. Dr. K.K Jha; Mustfa Ali

Volume : IX, Issue : II, February - 2020

AN OBSERVATIONAL STUDY ON ETIOLOGICAL AND EPIDEMIOLOGICAL PROFILE OF CHRONIC LIVER DISEASE IN TERTIARY CARE HOSPITAL

Mohammad Amir Suhail, Ashish Kumar Verma, Dr. Amit Mishra, Prof. Dr. K. K Jha, Mustfa Ali

Abstract :

BACKGROUND: Chronic liver disease is most common in Moradabad, West Uttar Pradesh. Hepatitis C and alcohol are the main causes of Chronic Liver Disease associated with high morbidity. This study in calculated evaluated etiology and epidemiological profile on Chronic Liver Disease in tertiary care hospital. MATERIALS AND METHOD: The patients, who met the inclusion and exclusion criteria, were enrolled in the study. The relevant data such as demographic details, laboratory data, etiological profile, epidemiological data, and social history, were collected from the medical record of the patient and results were analyzed. Result: During six months of study period, a total no.126 of patients of chronic liver disease were evaluated and from results we found that the majority of the patients were males 84(67%), female patient 42(33%) and above 41 years 69(55%) Ascites was the most common clinical presentation in Chronic liver disease (n=83; 65%) fallowed by jaundice (n=2o; 16%) and esophageal varices (n=63;50%) in this population. Out of 126 patients 41 (33%) had a history of alcohol consumption (chronic alcoholic), 41 were male (regularly). HCV was the major cause implicated in 45% (n=57) followed by HBV+HCV 13% (n= 18) of population. HCV was major etiologic factor of chronic liver disease followed by alcohol consumption as the secondary one. Of these the ethanol HCV 57 patients (45%), Alcohol 41 (33 %), (table no.6), DM 15 (12%) is a cofactor of chronic liver disease which played a role as starting cause of CLD. CONCLUSION: The data obtained in this study stated that male patients were found to be much prone to the development of the disease at the age of 41–60 years. The availability of risk towards disease was found to be 67% in rural than 33% in urban areas. The aim of the study was to provide an important and essential view for social and medical infect & to make people aware of the HCV and alcohol disease. The road show and campaigning were suggested to be planned and organized for the purpose.