ANALYSIS FOR THE DETECTION OF FREQUENCY OF Y CHROMOSOME MICRODELETIONS IN THE AZFa, AZFb and AZFc REGION IN DIFFERENT INFERTILE GROUPS OF NORTH EAST INDIAN POPULATION.

Anannya Gogoi; Rita Mahanta; Purnali Nath Barbhuiya; Samhita Roy; Pramod Sharma; Giasuddin Ahmed

Volume : VI, Issue : IV, April - 2017

ANALYSIS FOR THE DETECTION OF FREQUENCY OF Y CHROMOSOME MICRODELETIONS IN THE AZFa, AZFb and AZFc REGION IN DIFFERENT INFERTILE GROUPS OF NORTH EAST INDIAN POPULATION.

Anannya Gogoi, Rita Mahanta, Purnali Nath Barbhuiya, Samhita Roy, Pramod Sharma, Giasuddin Ahmed

Abstract :

The present study was undertaken to determine the frequency of AZF deletions in infertile men with azoospermia, cryptozoospermia, oligozoospermia, asthenozoospermia, teratozoospermia, oligoasthenozoospermia and asthenoteratozoospermia of North East India. In our study, Five hundred infertile patients and One hundred fertile men were screened for Y chromosome microdeletions.No microdeletions were detected in fertile men. Among 500 infertile men,123(24.6%) had azoospermia, 10 (2%) had cryptozoospermia, 103 (20.6%) had oligozoospermia, 112 (22.4%) had asthenozoospermia, 32 (6.4%) were teratozoospermia, 84 (16.8%) had oligoasthenozoospermia and 36 (7.2%) had asthenoteratozoospermia.According to our findings it was observed that the frequency in AZFc region is highest, followed by AZFa region and AZFc region in both blood and semen samples.