Analysis of Phytochemical Constituents And Antimicrobial Activities of Wedelia Chinensis Against Pathogens

Arumugam Durga; Rathinasamy Regina Mary

Volume : III, Issue : VIII, August - 2014

Analysis of Phytochemical Constituents And Antimicrobial Activities of Wedelia Chinensis Against Pathogens

Arumugam Durga, Rathinasamy Regina Mary

Abstract :

The present study was to evaluate the antimicrobial properties of solvent extracts from leaf and stem of Wedelia chinensis. The ethylacetate, acetone, methanol and hexane extract of medicinal plant were evaluated against Staphylococcus aureus, Bacillus subtilis, Pseudomonas aeruginosa, Klebsiella pneumoniae and Escherichia coli by using well diffusion assay. The leaf extract showed maximum antimicrobial activity against Bacillus subtilis (16.4�0.7) and lowest activity against Escherichia coli (9.4�0.6) compared with ciprofloxacin. The stem extract showed maximum antimicrobial activity against Staphylococcus aureus (15.3�0.8) and lowest activity against Pseudomonas aeruginosa (6.3�0.5) compared with ciprofloxacin (10mcg,). The antimicrobial activity could be confirmed in most species used in traditional medicine in South India. Nevertheless, traditional knowledge might provide some leads to elucidate potential candidates for future development of new antibiotic agents.