Volume : VI, Issue : IV, April - 2017

Analytic study of gastrointestinal tumours

Dr Mahesh M. Pukar, Dr Ajay Mahendra Tiwari

Abstract :

 Background: GIST was introduced as a diagnostic term in 1983[1]. Until the late 1990s, many non–epithelial tumours of the gastrointestinal tract were called “gastrointestinal stromal tumours.”  GISTs are a subset of mesenchymal tumours; represent the most common mesenchymal neoplasm of GI tract. [6] 

Aims and Objectives: To study the various location of the GIST at various parts of GI tract.

Introduction: Gastrointestinal tumours are most common mesenchymal neoplasms of the gastrointestinal tract. GISTs arise in the smooth muscle pacemaker intestinal cell of Cajal (ICC)^[1]. GISTs occur in the stomach and small intestine with rare occurrence in the rectum (5%), colon (1%), oesophagus and appendix. The diagnosis of GIST is currently based on morphologic features and immune–histochemical demonstration of KIT (CD 117)[2].

Material and method: This study was performed in January 2015 to December 2016 at Dhiraj General Hospital Vadodara.                                                                                          Discussion: GISTs occurs in the entire gastrointestinal tract, A great majority of them occurs in the stomach (60 – 70 %), small intestine (25 – 35 %), with rare occurrence in the colon(1%) and rectum (5%), oesophagus (<2%) and appendix. They are rarely found in omentum and mesentery. GISTs are characterised by various symptoms abdominal pain, nausea, vomiting, GI bleeding and lump in abdomen [2].                                                                                                          Results: Male predominance was found in this study. Diagnosis was made based on clinical findings, ultrasonography, CT scan of abdomen, and based on intra–operative findings and postoperative histopathological and immunohistochemistry findings. It is estimated that incidence of GISTs is approximately 10 – 20 per million peoples, per year.                                                                                                             Conclusion: This study shows male predominance, out of seven cases there were six male and one female patient. CT scan is ideal in defining endoluminal and exophytic extent of the tumours. The clinical presentation of GIST is variable but the most usual symptoms include the presence of mass or bleeding. Surgical resection of the local disease is the mainstay therapy.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Dr Mahesh M. Pukar, Dr Ajay Mahendra Tiwari, Analytic study of gastrointestinal tumours, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : VOLUME-6 | ISSUE-4 | APRIL‾2017

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