Antimicrobial Drug Possibility from Marine Macroalgae & selected Flora from Sunderban Delta

Madhumita Mukherjee; Reshma Sarkar

Volume : IV, Issue : V, May - 2015

Antimicrobial Drug Possibility from Marine Macroalgae & selected Flora from Sunderban Delta

Madhumita Mukherjee, Reshma Sarkar

Abstract :

Marine organisms are a rich source of structurally novel and biologically active metabolites. As a result of evolving resistance of microorganisms to existing antibiotics, there is an increasing need for newer antibiotics, the present study was carried out to investigate the antimicrobial potentiality of the marine algae Enteromorpha intestinalis ,Catenella impudica, Ulva sp.against strains of Gram positive, Gram negative bacteria such as Viio chlolerae ,Enterococcus faecalis ,Shigella boydii, Bacillus cereus, Pseudomonas aeruginosa, Staphylococcus aureus organisms that cause diseases and disorders in man, animals and plants. As for the mangroves of Indian Sunderbans such as Acanthus illicifolius, Heritiera fomes, Aegiceras corniculatum, Xylocarpus granatum, Sonneretia apetala, Ceriops decandra, test organisms include, Bacillus subtilis, Staphylococcus aureus,Streptococcus pneumoniae, Enterococcus faecalis and Micrococcus luteus among the gram positive bacteria and from gram negative bacteria Proteus mirabilis ,Salmonella typhi, Shigella flexineri, Viio cholerae, Escherichia coli, Klebsiella pneumoniae and Pseudomonas aeruginosa ,Aeromonas hydrophilia. Crude extracts revealed a wide range of antimicrobial activity against tested pathogens .The overall antimicrobial activity assessed from the above results indicates the presence of active constituents in the extractions of seaweeds which can be exploited for the production of lead molecules which are of use in pharmaceutical industry