IJSR - International Journal of Scientific Research

Dr. Sampa Dutta Gupta; Dr. Samarendra Nath Samui; Dr. Sushovan Chakraborty; Dr. Aritra Bhattacharya; COL. (Dr) A K Singh

Volume : VI, Issue : IV, April - 2017

Assessment of insulin sensitivity in obese, nondiabetic subjects undergoing infra umbilical abdominal surgeries

Dr. Sampa Dutta Gupta, Dr. Samarendra Nath Samui, Dr. Sushovan Chakraborty, Dr. Aritra Bhattacharya, Col. Dr A K Singh

Abstract :

Aim: To assess the pre–operative insulin sensitivity status in adult female with BMI more than 30kg/mt², posted for infra–umbilical abdominal surgeries under anaesthesia. CBG level before arrival in the OT prior to any intervention .

Patients & Methods: This prospective, observational study was done on 100 non–diabetic obese patients having BMI more than 30 kg/m², posted for elective infraumbilical abdominal surgeries under anaesthesia. Fasting insulin and fasting blood glucose estimation done before arrival in the OT prior to any intervention.

Insulin sensitivity status were calculated by homeostatic model assessment(HOMA) score.

Insulin resistance was considered when HOMA score>2.1

Results: 42 % of subjects were impaired found with impaired fasting glucose level, 67% of patients were detected as insulin resistance.

Conclusion: A significant section of obese population has abnormal insulin glucose homeostasis manifested as impaired fasting glucose, insulin resistance, which needs to be taken care off for better anaesthetic technique to prevent deterioration of insulin sensitivity status of obese patients.