Assessment of  pre and post operative lipid and lipoproteins in Breast carcinoma Patients of kancheepuram district, Tamilnadu, India

B.Prabasheela

Volume : III, Issue : XII, December - 2014

Assessment of pre and post operative lipid and lipoproteins in Breast carcinoma Patients of kancheepuram district, Tamilnadu, India

B. Prabasheela

Abstract :

Breast cancer is considered as disease of opulence which usually funnels to high fat consumption and obesity. Hence the study aimed to evaluate the lipid and lipoproteins level in histopathologically proven east cancer patients before and after surgery in comparison with age matched healthy control. Cholesterol were estimated by cholesterol oxidase method, Triglycerides by glycerol phosphate oxidase and HDL, LDL , VLDL by precipitation method. The cholesterol level was found to decrease after surgery as compared to before surgery. In both the cases, the level of cholesterol showed a significant increase (P< 0.05, P=0.0110) compared to control. The levels of Triglycerides (TG) and HDL - cholesterol were found to increase significantly before and after surgery when compared to control and their levels after surgery were found to decrease when compared before mastectomy. In both the cases, their levels were found to increase significantly (P<0.05, P = 0.0050, 0.0070). The level of LDL - cholesterol were found to be insignificant before and after surgery when compared to control (P>0.05, P=0.3822). The levels of VLDL were found to be highly significant before and after surgery in comparison with control but there is no significant change before and after surgery. The present work reflects disturbance in lipid metabolism as risk factor in east cancer and also translated the benefits of surgery in reducing east cancer risk and mortality.