Volume : VIII, Issue : VI, June - 2019
Assessment of salivary and serum alkaline phosphatase level in type 2 diabetes mellitus with periodontitis patients.
Zhahid Hassan, Afreen Nadaf, Sonia Gupta, Romshi Raina
Abstract :
Background: Oral health and general health are interdependent and of the classic example of this symbiotic relationship is that of Periodontal health and the Diabetes mellitus. Diabetes mellitus, play a crucial role in the progression of periodontal inflammatory conditions. Alkaline phosphatase (ALP) enzyme plays a significant role in gingival inflammation and bone resorption. Aim: To compare the serum and salivary alkaline phosphatase levels in chronic periodontitis patients with or without type 2 diabetes mellitus. Materials and Methods: The study consisted of a total of 45 individuals which were allocated to three groups: Group I (healthy individual), Group II (Chronic periodontitis without diabetes mellitus type 2) and Group III (Chronic periodontitis with type 2 diabetes mellitus). The serum and unstimulated saliva were collected from all patients in aseptic condition and samples were analyzed for alkaline phosphatase level using AVANTOR™ Benesphera ALP Kit by fully automated analyzer. Results: The concentration of serum and salivary alkaline phosphatase were significantly high in patients with chronic periodontitis with type 2 diabetes mellitus. Conclusion: Alkaline phosphatase can prove a valuable clinical diagnostic biomarker in periodontal diseases.
Keywords :
Alkaline phosphatase chronic periodontitis type II diabetes mellitus alveolar bone loss biomarker saliva
Article:
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DOI : 10.36106/ijsr
Cite This Article:
ASSESSMENT OF SALIVARY AND SERUM ALKALINE PHOSPHATASE LEVEL IN TYPE 2 DIABETES MELLITUS WITH PERIODONTITIS PATIENTS., Zhahid Hassan, Afreen Nadaf, Sonia Gupta, Romshi Raina INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-6 | June-2019
Number of Downloads : 173
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ASSESSMENT OF SALIVARY AND SERUM ALKALINE PHOSPHATASE LEVEL IN TYPE 2 DIABETES MELLITUS WITH PERIODONTITIS PATIENTS., Zhahid Hassan, Afreen Nadaf, Sonia Gupta, Romshi Raina INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-6 | June-2019
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