Assessment of serum liver enzymes levels in hypothyroid and hyperthyroid subjects in indian population

Volume : IV, Issue : IV, April - 2015

Pallavi Singh, Dr. G. G. Kaushik, Priyanka Singh

The thyroid gland is essential for metabolism and normal function of body cells including the liver cells. It helps

in the development and maturation of the hepatocytes and other body cells and tissues. This study enrolled a total of

100 patients with thyroid gland diseases hyperthyroid and hypothyroid diseases. The activities of the enzyme GGT, ALP, AST and ALT were

evaluated in these diseases state and were compared with normal healthy thyroid gland. There was highly significant increase and decrease

in the activity of GGT, ALP, AST and ALT in hyperthyroid and hypothyroid patients (P < 0.001) respectively when compared with third group

normal. The emerging evidence suggests that abnormal LFTs may be a marker for diagnosis of thyroid dysfunction.