Volume : VII, Issue : III, March - 2018
ASSOCIATION BETWEEN IRISIN AND GAMMA GLUTAMYL TRANSFERASE IN NORMAL AND TYPE 2 DIABETICS
G. G. Kaushik, Monika Dadheech, Mahesh Sharma
Abstract :
The aim of study was to evaluate and compare serum Irisin and Gamma Glutamyl Transferase (GGT) activity in type 2 diabetic patient (T2D) and in normal individual. In this case control study, age and sex matched 100 diagnosed cases of type 2 diabetes mellitus were compared with 100 healthy participants at Jawaharlal Nehru Medical College & Associated Group of Hospitals, Ajmer (Rajasthan). Levels of GGT were significantly higher (28.8 ± 8.0 vs 48.0 ± 10.7 IU/Lt.) and levels of Irisin were lower (214.9 ± 28.4 vs 202.2 ± 10.5 ng/ml) in T2D patients (P value < 0.001). GGT was found to be negatively correlated with Irisin (r = –0.946) in T2D patients and positively correlated with Irisin (r = 0.810) in healthy controls. In our study we found myokine Irisin level decreasing gradually with the progression of T2D and increase in GGT level in diabetics in response to oxidative stress.
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DOI : 10.36106/ijsr
Cite This Article:
G.G. Kaushik, Monika Dadheech, Mahesh Sharma, ASSOCIATION BETWEEN IRISIN AND GAMMA GLUTAMYL TRANSFERASE IN NORMAL AND TYPE 2 DIABETICS, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-3 | March-2018
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G.G. Kaushik, Monika Dadheech, Mahesh Sharma, ASSOCIATION BETWEEN IRISIN AND GAMMA GLUTAMYL TRANSFERASE IN NORMAL AND TYPE 2 DIABETICS, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-3 | March-2018
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