Association of Typhoid Fever with Hepatitis A and Hepatitis E Viral Infections: A South Indian Perspective

Dr. S. Nikhat Sheerin; Dr. Mohammed Nasaruddin; Dr. V.V. Shailaja; Dr. S. Rajeshwar Rao

Volume : VII, Issue : XII, December - 2018

Association of Typhoid Fever with Hepatitis A and Hepatitis E Viral Infections: A South Indian Perspective

Dr. S. Nikhat Sheerin, Dr. Mohammed Nasaruddin, Dr. V. V. Shailaja, Dr. S. Rajeshwar Rao

Abstract :

Introduction: Endemic, enteric infectious agents continue to wreak havoc on the health of communities in our country. The present study was undertaken with the aim of elucidating the association of Typhoid fever with Hepatitis A (HAV) and Hepatitis E (HEV) viral infections as there is a paucity of data regarding the prevalence of concurrent infections with these pathogens from our region.

Materials and Methods: Of the serum specimens received during Feuary – March 2018, 100 samples were routinely tested by Widal tube agglutination method. The same specimens were analysed for the presence of HAV and HEV IgM antibodies by ELISA.

Results: The prevalence of typhoid, HAV and HEV in the study population was 3 %, 1% and 3% respectively while co–infection with typhoid and HEV was found in 1% of cases.

Conclusions: There is a need to conduct similar studies but on a larger scale to correctly estimate the burden of co–infections with common enteric pathogens.