Association Of Vitamin D Deficiency And Erectile Dysfunction In Young Males – A Single Institutional Study.

DR SURYA KANT CHOUBEY; DR GOTAM PIPARA; DR SAURABH MITTAL

Volume : VI, Issue : XII, December - 2017

Association Of Vitamin D Deficiency And Erectile Dysfunction In Young Males – A Single Institutional Study.

Dr Surya Kant Choubey, Dr Gotam Pipara, Dr Saurabh Mittal

Abstract :

Background – Erection is a vascular event and Erectile Dysfunction (ED) is thought to be an important indicator of silent cardiovascular disease (CVD). Patients who have ED have an increased prevalence of endothelial dysfunction and (Vitamin D) VD improves endothelial dysfunction^.Low VD levels may result in reduced NO synthesis. Though the association between VD and CVD and its manifestations like hypertension, Peripheral vascular disease (PVD), Coronary artery disease (CAD) and heart failure is well established, there are no studies on direct association between patients having VD deficiency and ED in the absence of CVD.

Materials and methods – Young males aged between 20– 40 years who presented to urology outpatient clinic at St Johns medical college and hospital, Bangalore , Karnataka , India with complains of erectile dysfunction , had vitamin D deficiency without any cardiovascular risk factors between January 2015 to January 2017 were considered for the study. They were randomized into two groups and treated with Tadalafil in both. Group A was given vitamin D supplementation while Group B was not .They were reassessed at 6 weeks with IIEF score.

Results – There was significant improvement in the IIEF scores in the cohort of patients treated with vitamin D and Tadalafil compared to the cohort that was treated with Tadalafil and placebo.

Conclusion – Low vitamin D levels are associated with ED. Hence, it is a potentially modifiable risk factor in men who present with ED and must be evaluated.