Association of Vitamin D Deficiency with Hypothyroidism among population attending North Bengal Medical College and Hospital

Anup Kumar Debsinha; Krishna Chandra Sarkar; Shiuli Roy (Adak); Arup Kumar Banerjee; Anil Kumar

Volume : VII, Issue : VII, July - 2018

Association of Vitamin D Deficiency with Hypothyroidism among population attending North Bengal Medical College and Hospital

Anup Kumar Debsinha, Krishna Chandra Sarkar, Shiuli Roy Adak , Arup Kumar Banerjee, Anil Kumar

Abstract :

Background: Vitamin D deficiency is health problem which is prevalent globally. People require sufficient levels of Vitamin D in their blood for regulation of calcium metabolism in body for normal physiological actions. Very few governments and national or international organization have given much importance on the vitamin D deficiency or declared it a public health problem.

Objectives:There is a high prevalence of hypothyroidism and calcium deficiency in Indian population .Vitamin D deficiency is one of the major causes of calcium deficiency in our body. With this fact we found an opportunity to study the association between hypothyroidism and Vitamin D deficiency if any, among population of sub–Himalayan region of West Bengal attending North Bengal Medical College and Hospital.

Material and Methods:120 young and adult individuals between the age group 15 to 45 years comprising 60 number as control (n=60; 26 male and 34 female) and 60 as case (n=60; 24 male and 36 female) were taken in the study. Serum fT₃, fT₄, TSH and 25(OH) vitamin D levels were estimated using ELISA method. Patients having serum TSH>10 mIU/ml or serum TSH levels between 6 to 10 mIU/ml along with decreased serum fT₃&/or fT₄levels were diagnosed as hypothyroid cases. Statistical analysis was done by SPSS.

Results:Serum 25(OH) Vitamin D was significantly lower in hypothyroid patients (13.30 � 3.84 ng/ml) compared to controls (32.36� 5.88 ng/ml), p< 0.001. There was insignificantly decreased levels of Serum 25(OH) Vitamin D in females than male patients (t=.138, p>0.05).

Conclusion:The study indicates that patients with hypothyroidism are frequently associated with vitamin D deficiency which suggests that they need routine screening and vitamin D supplementation along with thyroid hormone replacement therapy.

Place of study: OPD and IPD of North Bengal Medical College and Hospital, West Bengal, India.