Atypical meningiomas: The Archetypical and Inferences

Alqroom Rami; Aldrous Rafeed; Abu–nowar Hussam; Alshurbaji Duaa; Sha�ban Firas; Al Shurbaji Amer

Volume : VI, Issue : IX, September - 2017

Atypical meningiomas: The Archetypical and Inferences

Alqroom Rami, Aldrous Rafeed, Abu Nowar Hussam, Alshurbaji Duaa, Sha Ban Firas, Al Shurbaji Amer

Abstract :

Impetus: Meningiomas are the mostly reported intracranial tumors, represent one third of all primary ain neoplasms in adults.

Objectives: In this analysis, we investigated outcomes of atypical meningioma diagnosed at a single institution. Special emphasis has been devoted to demographic features, predictive radiological signs, the concomitant factors predictive of tumor atypia with focus on clinical consequences, histological alterations, and risk factors related to the tumor treatment itself.

Patients and Methods: This retrospective study was conducted by reviewing histopathologic reports of all atypical meningiomas diagnosed and treated at King Hussein Medical Center, between January 2004 and January 2015. Demographic features; sex, age, tumor location, size of tumor, resection extent, and post–operative history of radiation therapy, and recurrence were documented.

Preoperative radiology reports were used to confirm tumor location and size based on largest single dimension. Extent of resection was based on surgical operative notes and post–operative imaging.

Results: Nighty–two patients showed atypical meningioma grade II. No gender predominance, young age at presentation, same topographical localization with grade one. All patients received adjuvant radiotherapy, recurrence noted in 19–patients.

Conclusion: Although the vast majority of meningiomas are benign, higher histological grade still reported with high frequency. The archetypical demographics of these tumors; no gender predominance, young age group, gross total resection is crucial for recurrence, adjuvant radiotherapy is still controversial.