Bacteriological Profile and Antimicrobial  Resistance Pattern in Patients Undergoing  Mechanical Ventilation in a Tertiary Care  Hospital, Navi Mumbai

Rakesh Kumar Mukhia; Dr. Anahita V. Bhesania Hodiwala; B.L. Chaudhary; Rakesh Pd.Sah

Volume : II, Issue : VII, July - 2013

Bacteriological Profile and Antimicrobial Resistance Pattern in Patients Undergoing Mechanical Ventilation in a Tertiary Care Hospital, Navi Mumbai

Rakesh Kumar Mukhia, Dr. Anahita V. Bhesania Hodiwala, B. L. Chaudhary, Rakesh Pd. Sah

Abstract :

The objective of this study was to know the frequency of VAP, causative bacteria and antibiotic sensitivity pattern of patients undergoing mechanical ventilation in hospital ICU. Total 125 clinically suspected VAP cases were studied. The frequency of VAP in the study is 36%. The most common bacteria isolated were Gram-negative organisms i.e. Acinetobacter species, Pseudomonas species, Klebsiella species and Escherichia coli. Susceptibility pattern of all Gram-negative organisms isolated from ETA (endotracheal aspirates) of VAP cases showed sensitivity to Amikacin and Ceftazidime (62.3%), Gentamycin (57.4%). Susceptibility pattern of all Gram-positive organism isolated from ETA of VAP cases showed 100% sensitivity to Vancomycin, Co-trimazole, Linezolid and Gentamicin. The overall outcome of VAPs could improve with the anti-microbial policies of individual centers. However, there are many controversies regarding the epidemiology, aetiology, diagnosis, therapy, resistance and the prognosis of VAP. Hence there is a need for larger studies.