Bacteriological Profile and Drug Resistance Pattern of Isolates of the Patients Admitted in Medical Intensive Care Unit of A Tertiary Care Hospital in Ahmadabad

Tanmay Mehta; Bimal Chauhan; Sanjay Rathod; Jayshree Pethani; Parul D. Shah

Volume : IV, Issue : II, February - 2015

Bacteriological Profile and Drug Resistance Pattern of Isolates of the Patients Admitted in Medical Intensive Care Unit of A Tertiary Care Hospital in Ahmadabad

Tanmay Mehta, Bimal Chauhan, Sanjay Rathod, Jayshree Pethani, Parul D. Shah

Abstract :

Introduction: Microbiological infection plays vital role in determining the outcome as well as cost and duration of the hospital stay for patients admitted in ICU setup. Therefore regular surveillance of important pathogens and its resistance pattern is mandatory. Objectives: The objective of this study was to find out the common organisms causing infection in patients admitted in medical ICU and to know resistance pattern of these isolates. Material & Method: During the period from November 2013 to Novemeber 2014, total of 537 samples from patients admitted in medical ICUs were collected and processed for culture, identification and antibiotic susceptibility testing according to CLSI recommendations. Results: Out of 583, 262 (48.78%) samples were culture positive. Most common organisms isolated were Acinetobacter species (30.92%) and Klebsiella sp. (29.77%) followed by Pseudomonas aeruginosa (22.9%) , E.coli (12.98%). PoymyxinB and colistin appear as most sensitive antibiotics. Carbapenems and Beta lactam-Betalactam inhibitor combination are showing emerging resistance now. Conclusion: This report reveals the bacteriology profile in patients in medical ICUs. Regular microbiological surveillance help in implementing better therapeutic strategies to reduce the high morbidity and mortality associated among the patients in critical care setting