Volume : IX, Issue : VI, June - 2020
Biochemical status of antioxidant enzymes as an indicator for complications in type -2 diabetes mellitus.
Devendra Nath Mishra, B. K. Agrawal, Arya Desh Deepak, Dhirendra Kumar Shukla, Kanchan Singh, Sadhna Ajay
Abstract :
Background: Diabetes mellitus (DM) is extremely common representing a significant global health problem. Diabetes mellitus (DM) is characterized by chronic hyperglycemia and impaired carbohydrate, lipid, and protein metabolism caused by complete insufficiency of insulin secretion. Diabetes is a disease with chronic low grade inflammation. This inflammatory milieu promotes atherosclerosis and gives rise to other complications in diabetes. Aim and objective: Assessment of antioxidant enzyme in type –2 diabetes mellitus with complications, without complications and controls. Material and Methods: A total of 100 patients, 50 – Type–2 Diabetes mellitus with complications, 50 without complications for the last one year and 50 normal healthy individuals were chosen as control group. Results: The results showed a mean values of Blood Sugar levels (F), Blood Sugar levels (PP), were significantly increased (P<0.0001) in type – 2 Diabetes mellitus With complications, T2 DM. without– complications as compared to control. Another mean values of SOD, glutathione peroxidase and glutathione Reductase were highly significantly decrease (P<0.0001) in T – 2 DM with complications, T – 2 DM without complications as compared to control.
Keywords :
Superoxide Dismutase Glutathione Peroxidase and Glutathione Reductase Type–2 Diabetes mellitus With Complications type–2 Diabetes mellitus Without – Complications hyperglycaemia
Article:
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DOI : 10.36106/ijsr
Cite This Article:
BIOCHEMICAL STATUS OF ANTIOXIDANT ENZYMES AS AN INDICATOR FOR COMPLICATIONS IN TYPE -2 DIABETES MELLITUS., Devendra Nath Mishra, B. K. Agrawal, Arya Desh Deepak, Dhirendra Kumar Shukla, Kanchan Singh, Sadhna Ajay INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-9 | Issue-6 | June-2020
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BIOCHEMICAL STATUS OF ANTIOXIDANT ENZYMES AS AN INDICATOR FOR COMPLICATIONS IN TYPE -2 DIABETES MELLITUS., Devendra Nath Mishra, B. K. Agrawal, Arya Desh Deepak, Dhirendra Kumar Shukla, Kanchan Singh, Sadhna Ajay INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-9 | Issue-6 | June-2020
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