C-reactive protein as a predictor of Left ventricular failure in acute myocardial infarction

Dr.Arumugam.M.A; Dr.Senthilkumar.R

Volume : VII, Issue : XI, November - 2018

C-reactive protein as a predictor of Left ventricular failure in acute myocardial infarction

Dr. Arumugam. M. A, Dr. Senthilkumar. R

Abstract :

Background: Various biochemical substances rise in the serum in patients with Acute MI. C–Reactive protein is helpful in diagnosis and also in assessing the complications and efficacy of thrombolytic therapy in Acute myocardial Infarction Aim of the study : To assess the correlation between C–reactive protein level and cardiac failure and risk of cardiac rupture in Acute myocardial infarction. Materials and method: 50 patients admitted for Myocardial infarction in ICCU with typical chest pain and definitive ECG changes of ST segment elevation in at least two leads. Vital parameters were recorded. Serial ECG charges were followed in all patients. Blood sample drawn between 6 and 12hrs , 14 to30 hrs, 24to 30 hrs and 48–60 hrs after the onset of chest pain .Fifth Sample drawn at the end of one week. The sample was tested for C–reactive protein level by latex agglutination test. 20 patients who attended the outpatient department were kept as control. Results: Study population :50 . Males:42 Females:8,Age group: 30 to 76 yrs. Inferior Wall:16 AnteriorWall:34 .C–reactive protein level started raising after 12 hrs in most of the patients. Conclusion: High Serum C–reactive protein levels correlate with development of Left ventricular failure in acute myocardial infarction. This study also predicts that no patient was at risk for subacute cardiac rupture since the peal values were not above 20mg/dl