IJSR - International Journal of Scientific Research

Sachin Rastogi; Pushpa Yadav; Madhulika Singh

Volume : VII, Issue : VI, June - 2018

Cadmium toxicity and its effect on the Histolopathology of liver and kidney of the fresh water teleost, Heteropneustes fossilis (Bloch)

Sachin Rastogi, Pushpa Yadav, Madhulika Singh

Abstract :

In this study, cadmiumchloride (CdCl₂) toxicity was studied in an experimental aquatic exposure.Heteropneustesfossilis (an air–eathing catfish) were chronically exposed to different concentration of CdCl₂(25, 50 and 75 mg/L) for 30 and 60 days. Morphological and histological changes in H.fossilis following the doses of CdCl₂were studied. Histopathologicalinvestigations revealed greater changes in liver and kidney tissues after chronic exposure. Necrosis of epithelial cells of renal tubules,Glomerular contraction and reduction of Bowman’s space were observed in the kidney tissue of exposed fish.Changes observed in the liver tissue post exposureincluded necrosis, degradation of hepatocytes, degeneration of blood vessels, distended sinusoids withpyknotic nuclei and vacuolation of cells. The degree of damage to the liver and kidney tissue was proportional to theconcentrations and duration of the CdCl₂ used.