Cerebral perfusion changes in Depression subjects using Single Photon Emission Computed Tomography

Dr. Gandikota Vishnu Vardhan; Dr. Pabbati Lokeswara Reddy

Volume : VII, Issue : II, February - 2018

Cerebral perfusion changes in Depression subjects using Single Photon Emission Computed Tomography

Dr. Gandikota Vishnu Vardhan, Dr. Pabbati Lokeswara Reddy

Abstract :

Background : Depression is a common psychiatric illness affecting all age groups with high life time prevalence. Psychiatry has started searching for a biological basis with recent advances in functional imaging techniques, like Single Photon Emission Computed Tomography to identify changes in cereal perfusion associated with psychiatric illness Aim and objectives: To study cereal perfusion changes in Recurrent Depressive Disorder subjects in different locations of ain using SPECT scan during depressive episode and comp� with normal subjects Material and Methods: Cross sectional, comparative and observational study at a tertiary care center with institutional ethics committee approval Results:. Significant difference in perfusion was noted only in left temporal region (p value < 0.03) in depression population when compared to control population Conclusion : Brain perfusion changes were observed in multiple ain regions, but significant only in Left Temporal region showing that perfusion pattern of ain has an association with depressive episode