Volume : VII, Issue : IX, September - 2018

Cholinesterase as Marker of Congenital Anomalies

Prasanta Saha Roy, Dr Abhra Ghosh

Abstract :

Increase incidence of congenital abnormalities in north–west India suggests the role of some environmental factor. As N–W India is predominantly an agricultural community and pesticides exposure are hypothesized to be one of the causative agents of it. The present study was planned to analyse the levels of cord blood cholinesterase in newborns with congenital anomalies.Thirty healthy newborns and thirty newborns with visible congenital anomalies are selected as control and cases respectively. Detailed history of present pregnancy were taken and detailed physical examination of babies were done. Five ml cord blood was collected from placental end of umbilical cord after delivery of baby and serum was separated and serum cholinesterase were estimated enzymatically.Serum cholinesterase levels were significantly decreased in babies with congenital anomalies as compared to healthy counterparts. Low cholinesterase levels can be caused by various agricultural and industrial pollutant in this region and might result in congenital anomalies in this region.

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Article: Download PDF   DOI : 10.36106/ijsr  

Cite This Article:

Prasanta Saha Roy, Dr Abhra Ghosh, Cholinesterase as Marker of Congenital Anomalies, INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-7 | Issue-9 | September-2018

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