Volume : VIII, Issue : XII, December - 2019

Clinical Correlation between Mean Corpuscle Volume and Serum B12 Level

Viral J Patel, Amit Maniyar

Abstract :

Dietary absence, especially B12 deficit is pretty general in India. The demonstration can array from anemia usually megaloblastic anemia as an premature indicator to neurological consequence that develop shortly. Appraisal of Mean Corpuscular Volume (MCV) as a showing bound has been extremely untrustworthy and deceptive .Our study aimed at Clinical Correlation between Mean Corpuscle Volume and Serum B12 Level. The study inhabitants consisted of 250 teenager aged 08–16 years leaving to schools in the rustic zone of the region. Those with olden times of hemolytic illness were barred in the study. The prevalence of vitamin B12 deficiency in rural areas was found to be 58.58% in adolescent school going girls. The B12 deficient population depicted significant association with vegetarian diet (p<0.001) and BMI (p=0.005). The sensitivity and specificity of MCV to screen out B12 deficiency were calculated to be 10.14% and 92.82% respectively. Accuracy of MCV as an indicator for B12 deficiency was estimated to be 45.05%. From all the above data, the percentage of subjects missed to be diagnosed for B12 deficiency of all deficient subjects was calculated to be 89.86%. It is concluded that normal Mean Corpuscular Volume (MCV) of an individual does not interpret that the serum B12 levels are also normal or high because in age group 21–30, 100% subjects, in age group 31–40, 84% subjects and in age group 41–50, 92% of the subjects did not have correlation between MCV and B12 levels. Hence, only MCV should not be used as a marker for determining B12 deficiency

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Article: Download PDF    DOI : 10.36106/ijsr  

Cite This Article:

CLINICAL CORRELATION BETWEEN MEAN CORPUSCLE VOLUME AND SERUM B12 LEVEL, Viral J Patel, Amit Maniyar INTERNATIONAL JOURNAL OF SCIENTIFIC RESEARCH : Volume-8 | Issue-12 | December-2019

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