IJSR - International Journal of Scientific Research

Dr. Hemeshwar Harshwardhan; Dr. Prashant Maheshwari

Volume : VI, Issue : V, May - 2017

Clinical outcomes of platelet rich plasma therapy in Osteoarthrosis knee

Dr. Hemeshwar Harshwardhan, Dr. Prashant Maheshwari

Abstract :

New studies focused on modern therapeutic methods which stimulate cartilage healing and repair the damage, including the use of platelet–rich plasma (PRP) as a cocktail of growth factors. This study has the purpose to present the use of PRP in management of early stage of knee Osteoarthrosis and its outcomes up to 12 month follow up.48 patients with 87 knees (22 male, 26 female) with Kellgren Lawrence grade 1, 2 and 3, aged between 50 to 65 years between Feb.2015 to December 2015 treated with 4ml of intra–articular PRP injections at 4 week interval in each affected knee and evaluated using WOMAC and VAS scores before treatment begins and at end of the 1st, 3rd, 6th and 12th month follow up.Improvement in WOMAC score for KL grade 1(15.82%), grade 2(17.93%), grade 3(11.92%) at end of 12 months follow up. Improvement in VAS score for KL grade 1(18.84%), grade 2(12.55%), grade 3(23.22%) at the end of 12 months follow up. Improvement is statistically significant with p value (<0.05) at 12 months follow up.The results of our study illustrated that the treatment with intra articular PRP injections is safe and effective in reducing pain and stiffness as well as improve knee function and quality of life in early stages of knee Osteoarthrosis. .