Clinical Profile and Outcome of Status Epilepticus patients admitted in PICU at tertiary care centre.

Dr. Sonali Bijjargi; Dr. Suhas G. Kumbhar; Dr. Mahesh Sale

Volume : VII, Issue : III, March - 2018

Clinical Profile and Outcome of Status Epilepticus patients admitted in PICU at tertiary care centre.

Dr. Sonali Bijjargi, Dr. Suhas G. Kumbhar, Dr. Mahesh Sale

Abstract :

Background: Status Epilepticus (SE) is a common life threatening neurological disorder that is essentially an acute, prolonged epileptic crisis.

Objectives: To study the clinical profile and outcome of Status Epilepticus patients admitted in PICU.

Setting & Study design: Retrospective cross sectional study.

Materials and Methods: 45 Patients case record of SE in the age group of 1 month to 16 years were included in the study over a period of 2 years. Clinical history, general and systemic examination, relevant investigations, duration of PICU stay and immediate outcome from the case records were considered.

Results: Mean age for the study population was found to be 6.03 years. Preponderance of male (69%) over female (31%) was observed. Aetiology included Acute symptomatic (44.4%), Remote symptomatic (42.4%), Feile, Idiopathic and progressive encephalopathy being (4.4%). Generalised tonic–clonic convulsion (GTC) was observed in 76% of SE patients while 22% had partial SE and 2% had myoclonic astatic epilepsy. 40% of patients had prior history of convulsion whereas 60% presented with SE as first episode of convulsion. Mean duration of PICU stay in all SE patients was found to be 5.1 days. In our study, mortality rate was found to be 18% and acute symptomatic cause were responsible for most of the deaths.

Conclusion: SE is a life threatening emergency with substantial morbidity and mortality. Patients with younger age and male sex are slightly more vulnerable to develop SE. Longer duration of SE and acute symptomatic aetiologies are independent predictors for poor outcome.